Indicated for Sleeplessness, Irritability, Toothache. Coffea cruda is a homeopathic remedy commonly used for sleeplessness, irritability, and toothache. Other indications include great sensitivity of the senses and affections that are the result of joyful surprises. The remedy is made unroasted coffee beans. Active ingredient: Coffea cruda [HPUS]. Inactive ingredients: Sucrose/lactose pellets.